Article
Polymorphic variation in the androgen receptor gene: association with risk of testicular germ cell cancer and metastatic disease.
European journal of cancer (Oxford, England : 1990) - 1 Feb 2011
Västermark Åke, Giwercman Yvonne Lundberg, Hagströmer Oskar, Rajpert De-Meyts Ewa, Eberhard Jakob, Ståhl Olof, Cedermark Gabriella Cohn, Rastkhani Hamideh, Daugaard Gedske, Arver Stefan, Giwercman Aleksander
Abstract excerpt
Increasing incidence of testicular germ cell cancer (TGCC) is most probably related to environment and lifestyle. However, an underlying genetic predisposition may play a role and since sex steroids are assumed to be important for the rise and progression of TGCC, a study of androgen receptor (AR) gene polymorphisms in relation to the risk, histological type and progression of TGCC was undertaken. In 367 TGCC...
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