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Article

Beyond genome-wide scan: Association of a cis-regulatory NCR3 variant with mild malaria in a population living in the Republic of Congo.

PloS one - 1 Jan 2017

Baaklini Sabrina, Afridi Sarwat, Nguyen Thy Ngoc, Koukouikila-Koussounda Felix, Ndounga Mathieu, Imbert Jean, Torres Magali, Pradel Lydie, Ntoumi Francine, Rihet Pascal

Abstract excerpt

Linkage studies have revealed a linkage of mild malaria to chromosome 6p21 that contains the NCR3 gene encoding a natural killer cell receptor, whereas NCR3-412G>C (rs2736191) located in its promoter region was found to be associated with malaria in Burkina Faso. Here we confirmed the association of rs2736191 with mild malaria in a Congolese cohort and investigated its potential cis-regulatory effect. Luciferase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29121672
DOI: 10.1371/journal.pone.0187818
PMCID: PMC5679660

Genes

NCR3
RUNX3
STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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