Article
Genetic control of visceral leishmaniasis in a Sudanese population: candidate gene testing indicates a linkage to the NRAMP1 region.
Genes and immunity - 1 Mar 2003
Bucheton B, Abel L, Kheir M M, Mirgani A, El-Safi S H, Chevillard C, Dessein A
Abstract excerpt
There is some evidence showing that genetic factors are involved in human susceptibility to parasitic diseases such as schistosomiasis and malaria. Studies have shown that the Nramp1 and H-2 genes are implicated in the control of Leishmania donovani infection in mice. We sought genetic loci involved in the control of susceptibility to visceral disease caused by L. donovani in humans. We studied 37 families with...
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