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Article

Evidence for epistasis between hemoglobin C and immune genes in human P. falciparum malaria: a family study in Burkina Faso.

Genes and immunity - 1 Sept 2011

Atkinson A, Barbier M, Afridi S, Fumoux F, Rihet P

Abstract excerpt

Hemoglobin C (HbC) has been recently associated with protection against Plasmodium falciparum malaria. It is thought that HbC influences the development of immune responses against malaria, suggesting that the variation at the HbC locus (rs33930165) may interact with polymorphic sites in immune genes. We investigated, in 198 individuals belonging to 34 families living in Burkina Faso, statistical interactions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21451558
DOI: 10.1038/gene.2011.19

Genes

LTA
NCR3
TNF

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