Article
Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus.
Genes and immunity - 1 Oct 2007
Khor C C, Vannberg F O, Chapman S J, Walley A, Aucan C, Loke H, White N J, Peto T, Khor L K, Kwiatkowski D, Day N, Scott A, Berkley J A, Marsh K, Peshu N, Maitland K, Williams T N, Hill A V S
Abstract excerpt
Four cytokine receptor genes are located on Chr21q22.11, encoding the alpha and beta subunits of the interferon-alpha receptor (IFNAR1 and IFNAR2), the beta subunit of the interleukin 10 receptor (IL10RB) and the second subunit of the interferon-gamma receptor (IFNGR2). We previously reported that two variants in IFNAR1 were associated with susceptibility to malaria in Gambians. We now present an extensive...
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