Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parent-of-origin-environment interactions in case-parent triads with or without independent controls.

Annals of human genetics - 1 Mar 2018

Gjerdevik Miriam, Haaland Øystein A, Romanowska Julia, Lie Rolv T, Jugessur Astanand, Gjessing Håkon K

Abstract excerpt

With case-parent triad data, one can frequently deduce parent of origin of the child's alleles. This allows a parent-of-origin (PoO) effect to be estimated as the ratio of relative risks associated with the alleles inherited from the mother and the father, respectively. A possible cause of PoO effects is DNA methylation, leading to genomic imprinting. Because environmental exposures may influence methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cleft Palate
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Linear Models

Share to Models, Genetic

Share to Parents

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 29094765
DOI: 10.1111/ahg.12224
PMCID: PMC5813215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parent-of-origin-environment interactions in case-parent triads with or without independent controls.PMID 29094765Read ↗

Genome-wide analysis of parent-of-origin interaction effects with environmental exposure (PoOxE): An application to European and Asian cleft palate trios.Semantic proximity Read ↗

Genome-wide analysis of parent-of-origin effects in non-syndromic orofacial clefts.Semantic proximity Read ↗

Gene-methylation interactions: Discovering region-wise DNA methylation levels that modify SNP-associated disease riskSemantic proximity Read ↗

Inference of gene-environment interaction from heterogeneous case-parent triosSemantic proximity Read ↗

Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts.Semantic proximity Read ↗

Gene-methylation interactions: discovering region-wise DNA methylation levels that modify SNP-associated disease risk.Semantic proximity Read ↗

POIROT: a powerful test for parent-of-origin effects in unrelated samples leveraging multiple phenotypes.Semantic proximity Read ↗

Review of statistical methodologies for the detection of parent-of-origin effects in family trio genome-wide association data with binary disease traits.Semantic proximity Read ↗

Detection of parent-of-origin specific expression quantitative trait loci by cis-association analysis of gene expression in trios.Semantic proximity Read ↗

Efficient genome-wide association testing of gene-environment interaction in case-parent trios.Semantic proximity Read ↗

A model for family-based case-control studies of genetic imprinting and epistasis.Semantic proximity Read ↗

Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.