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Article

Detection of parent-of-origin specific expression quantitative trait loci by cis-association analysis of gene expression in trios.

PloS one - 1 Jan 2012

Garg Paras, Borel Christelle, Sharp Andrew J

Abstract excerpt

Parent-of-origin (PofO) effects, such as imprinting are a phenomenon in which homologous chromosomes exhibit differential gene expression and epigenetic modifications according to their parental origin. Such non-Mendelian inheritance patterns are generally ignored by conventional association studies, as these tests consider the maternal and paternal alleles as equivalent. To identify regulatory regions that show...

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Identifiers

PMID: 22912676
DOI: 10.1371/journal.pone.0041695
PMCID: PMC3422236

Genes

PEG10
SRRT
TRAPPC9

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