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Article

Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome.

EBioMedicine - 1 Dec 2021

Zeng Yanni, Amador Carmen, Gao Chenhao, Walker Rosie M, Morris Stewart W, Campbell Archie, Frkatović Azra, Madden Rebecca A, Adams Mark J, He Shuai, Bretherick Andrew D, Hayward Caroline, Porteous David J, Wilson James F, Evans Kathryn L, McIntosh Andrew M, Navarro Pau, Haley Chris S

Abstract excerpt

BACKGROUND: parent-of-origin effects (POE) play important roles in complex disease and thus understanding their regulation and associated molecular and phenotypic variation are warranted. Previous studies mainly focused on the detection of genomic regions or phenotypes regulated by POE. Understanding whether POE may be modified by environmental or genetic exposures is important for understanding of the source of...

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Identifiers

PMID: 34883445
DOI: 10.1016/j.ebiom.2021.103730
PMCID: PMC8654798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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