Article

Gene-methylation interactions: Discovering region-wise DNA methylation levels that modify SNP-associated disease risk

2019-04-12

Abstract excerpt

The genetic code is tightly linked to epigenetic instructions as to what genes to express, and when and where to express them. The most studied epigenetic mark is DNA methylation at CpG dinucleotides. Today’s technology enables a rapid assessment of DNA sequence and methylation levels at a single-site resolution for hundreds of thousands of sites in the human genome, in thousands of individuals at a time. Recent y...

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Literature Corpus work: e0ef8c34-d02d-5483-be3a-ea6cf67ccb21
DOI: 10.1101/593053

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