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Article

Circulating B cells in type 1 diabetics exhibit fewer maturation-associated phenotypes.

Clinical immunology (Orlando, Fla.) - 1 Oct 2017

Hanley Patrick, Sutter Jennifer A, Goodman Noah G, Du Yangzhu, Sekiguchi Debora R, Meng Wenzhao, Rickels Michael R, Naji Ali, Luning Prak Eline T

Abstract excerpt

Although autoantibodies have been used for decades as diagnostic and prognostic markers in type 1 diabetes (T1D), further analysis of developmental abnormalities in B cells could reveal tolerance checkpoint defects that could improve individualized therapy. To evaluate B cell developmental progression in T1D, immunophenotyping was used to classify circulating B cells into transitional, mature naïve, mature...

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Identifiers

PMID: 28951327
DOI: 10.1016/j.clim.2017.09.021
PMCID: PMC5673557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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