Article
Altered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA).
Clinical and experimental immunology - 1 Oct 2016
Radenkovic M, Silver C, Arvastsson J, Lynch K, Lernmark Å, Harris R A, Agardh C-D, Cilio C M
Abstract excerpt
Latent autoimmune diabetes of the adults (LADA) accounts for up to 12% of all patients with diabetes. Initially the disease resembles type 2 diabetes (T2D); however, the typical presence of β cell autoantibodies indicates an autoimmune basis of LADA. While dysfunctional regulatory T cells (Tregs ) have been implicated in autoimmune diabetes, these cells have been scarcely studied in LADA. The aim of this study...
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