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Article

Poor in vitro maturation and pro-inflammatory cytokine response of dendritic cells in children at genetic risk of type 1 diabetes.

Scandinavian journal of immunology - 1 Dec 2004

Skarsvik S, Tiittanen M, Lindström A, Casas R, Ludvigsson J, Vaarala O

Abstract excerpt

Type 1 diabetes (T1D) has been associated with an aberrant maturation of dendritic cells (DC). We studied the maturation of monocyte-derived DC in children with newly diagnosed T1D and in healthy children with genetic risk for T1D. Peripheral blood monocytes from children with newly diagnosed T1D (n = 12; mean age 13.2 years), children with human leukocyte antigen (HLA)-risk genotype of T1D (n = 7; mean age 12.7...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15584977
DOI: 10.1111/j.0300-9475.2004.01521.x

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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