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Article

Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease.

Frontiers in immunology - 1 Jan 2021

Amodio Giada, Mandelli Alessandra, Curto Rosalia, Rancoita Paola M V, Stabilini Angela, Bonfanti Riccardo, de Pellegrin Maurizio, Bosi Emanuele, Di Serio Clelia, Battaglia Manuela, Gregori Silvia

Abstract excerpt

Type 1 diabetes (T1D) is a chronic autoimmune disease resulting in progressive destruction of β-cells. Several factors affecting lymphocyte and antigen-presenting cells, including dendritic cells (DCs), contribute to defective maintenance of tolerance in T1D. DC-10 are a subset of human DCs involved in IL-10-mediated tolerance. A precise monitoring of DC-10 in the peripheral blood is possible thanks to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34659254
DOI: 10.3389/fimmu.2021.750162
PMCID: PMC8517474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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