Article
Multimerization rules for G-quadruplexes.
Nucleic acids research - 6 Sept 2017
Kolesnikova Sofia, Hubálek Martin, Bednárová Lucie, Cvacka Josef, Curtis Edward A
Abstract excerpt
G-quadruplexes can multimerize under certain conditions, but the sequence requirements of such structures are not well understood. In this study, we investigated the ability of all possible variants of the central tetrad in a monomeric, parallel-strand G-quadruplex to form higher-order structures. Although most of these 256 variants existed primarily as monomers under the conditions of our screen, ∼10% formed...
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