Article
Sequence Requirements of Intrinsically Fluorescent G-Quadruplexes.
Biochemistry - 17 Jul 2018
Majerová Tat'ána, Streckerová Tereza, Bednárová Lucie, Curtis Edward A
Abstract excerpt
G-Quadruplexes are four-stranded nucleic acid structures typically stabilized by GGGG tetrads. These structures are intrinsically fluorescent, which expands the known scope of nucleic acid function and raises the possibility that they could eventually be used as signaling components in label-free sensors constructed from DNA or RNA. In this study, we systematically investigated the effects of mutations in...
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