Article
Overlapping but distinct: a new model for G-quadruplex biochemical specificity.
Nucleic acids research - 26 Feb 2021
Volek Martin, Kolesnikova Sofia, Svehlova Katerina, Srb Pavel, Sgallová Ráchel, Streckerová Tereza, Redondo Juan A, Veverka Václav, Curtis Edward A
Abstract excerpt
G-quadruplexes are noncanonical nucleic acid structures formed by stacked guanine tetrads. They are capable of a range of functions and thought to play widespread biological roles. This diversity raises an important question: what determines the biochemical specificity of G-quadruplex structures? The answer is particularly important from the perspective of biological regulation because genomes can contain...
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