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Article

A sodium/potassium switch for G4-prone G/C-rich sequences.

Nucleic acids research - 11 Jan 2024

Luo Yu, Živković Martina Lenarčič, Wang Jiawei, Ryneš Jan, Foldynová-Trantírková Silvie, Trantírek Lukáš, Verga Daniela, Mergny Jean-Louis

Abstract excerpt

Metal ions are essential components for the survival of living organisms. For most species, intracellular and extracellular ionic conditions differ significantly. As G-quadruplexes (G4s) are ion-dependent structures, changes in the [Na+]/[K+] ratio may affect the folding of genomic G4s. More than 11000 putative G4 sequences in the human genome (hg19) contain at least two runs of three continuous cytosines, and...

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Identifiers

PMID: 37986223
DOI: 10.1093/nar/gkad1073
PMCID: PMC10783510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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