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G-quadruplex stabilization in the ions and maltose transporters inhibit <i>Salmonella enterica</i> growth and virulence

2018-06-27

Abstract excerpt

The G-quadruplex structure forming motifs have recently emerged as a novel therapeutic drug target in various human pathogens. Herein, we report three highly conserved G-quadruplex motifs (SE-PGQ-1, 2, and3) in genome of all the 412 strains of Salmonella enterica . Bioinformatics analysis inferred the presence of SE-PGQ-1 in the regulatory region of mgtA , presence of SE-PGQ-2 in the open reading frame of entA...

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Literature Corpus work
c052a56a-7984-5f63-acd8-b26049777039
DOI
10.1101/357046
Open publication

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G-quadruplex stabilization in the ions and maltose transporters inhibit <i>Salmonella enterica</i> growth and virulenceDOI 10.1101/357046
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