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Article

Associations of genetic variants of endothelin with cardiovascular complications in patients with renal failure.

BMC nephrology - 7 Sept 2017

Kao Chih-Chin, Cheng Shih-Ying, Wu Mei-Yi, Chien Shu-Chen, Lu Hsing-Fang, Hsu Yu-Wen, Zhang Yan-Feng, Wu Mai-Szu, Chang Wei-Chiao

Abstract excerpt

BACKGROUND: Cardiovascular (CV) complications are the main cause of death in end-stage renal disease (ESRD) patients. The high CV risks are attributable to the additive effects of multiple factors. Endothelin (EDN) is a potent vasoconstrictor and plays a role in regulating vascular homeostasis. However, whether variants of the EDN gene are associated with risks of CV events is not known. We conducted a study to...

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Identifiers

PMID: 28882114
DOI: 10.1186/s12882-017-0707-2
PMCID: PMC5590196

Genes

EDN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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