Article
Endothelin-1 rs9296344 associates with the susceptibility of childhood primary nephrotic syndrome.
Journal of clinical laboratory analysis - 1 Apr 2020
Zhang Ruifeng, Yang Huandan, Zhu Bingbing, Yuan Tingting, Peng Qianqian, Lv Juan, Qiu Shan, Zhou Suqin, Li Yan, Zhong Zhaowen
Abstract excerpt
BACKGROUND: Recently, the rs5370 single nucleotide polymorphisms (SNPs) of Endothelin-1 (EDN1) showed association with the susceptibility of childhood primary nephrotic syndrome (CPNS). This study aims to investigate potential relationships between other EDN1 SNPs and CPNS. METHODS: Seven SNPs (rs5370, rs10478723, rs1476046, rs1800541, , , and ) of the EDN1 gene were genotyped in 579...