Article
Association of single nucleotide polymorphisms in endothelin family genes with the progression of atherosclerosis in patients with essential hypertension.
Journal of human hypertension - 1 Nov 2007
Yasuda H, Kamide K, Takiuchi S, Matayoshi T, Hanada H, Kada A, Yang J, Miwa Y, Yoshii M, Horio T, Yoshihara F, Nakamura S, Nakahama H, Tei C, Miyata T, Kawano Y
Abstract excerpt
Endothelin-1 (ET-1) is a potent vasoconstrictive peptide and its activity is mediated by the receptors ET type A (EDNRA) and ET type B (EDNRB). Although ET-1 is thought to play an important role in the development of atherosclerosis, it remains unclear whether polymorphisms of ET-1 family genes, including the ET-1 gene (EDN1), EDNRA, EDNRB and the genes for endothelin converting enzymes 1 and 2 (ECE1 and ECE2),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.