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Article

The -974C>A (rs3087459) gene polymorphism in the endothelin gene (EDN1) is associated with risk of developing acute coronary syndrome in Mexican patients.

Gene - 1 Jun 2014

Vargas-Alarcon Gilberto, Vallejo Maite, Posadas-Romero Carlos, Juarez-Rojas Juan G, Martinez-Rios Marco Antonio, Peña-Duque Marco Antonio, Carrillo-Sanchez Silvia, Perez-Mendez Oscar, Fragoso José Manuel

Abstract excerpt

Endothelial dysfunction plays an essential role in the development and progression of atherosclerotic lesions. Endothelial nitric oxide synthase (eNOS) and endothelin-1 (ET-1) are considered important molecules in the endothelial dysfunction process. The aim of the present study was to evaluate t...

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Source

Identifiers

PMID: 24035903
DOI: 10.1016/j.gene.2013.09.003

Genes

EDN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24035903-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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