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Article

Association of endothelin-1 gene polymorphisms with essential hypertension in a Chinese population.

Genetics and molecular research : GMR - 6 Jul 2017

Fang Z, Li M, Ma Z, Tu G

Abstract excerpt

Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor and is involved in several vascular disorders such as hypertension. Its strong interaction with other vasoactive hormone systems suggests that the ET-1 gene (EDN1) is a potential candidate molecule that influences the risk of developing hypertension. Recently, two single nucleotide polymorphisms in EDN1 have been reported to be associated with...

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Identifiers

PMID: 28692114
DOI: 10.4238/gmr16037446

Genes

EDN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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