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Endothelin-1 Gene Polymorphisms rs5370, rs1476046, and rs3087459 are not Associated with Diabetic Nephropathy in Caucasians with Type 2 Diabetes Mellitus.

Folia medica - 1 Sept 2017

Šeruga Maja, Kariž Stojan, Makuc Jana, Završnik Matej, Cilenšek Ines, Gazdikova Katarina, Caprnda Martin, Kruzliak Peter, Petrovič Daniel

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) is a major microvascular complication of type 2 diabetes mellitus (T2DM). Several lines of evidence implicate the endothelin (ET) system in the pathophysiology of DN. The aim of the present study was to analyze if genetic polymorphisms of the ET-1 (EDN1) gene affect susceptibility to DN in Caucasians with T2DM. MATERIALS AND METHODS: The study population consisted of 651...

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PMID: 28976905
DOI: 10.1515/folmed-2017-0033

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EDN1

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Endothelin-1 Gene Polymorphisms rs5370, rs1476046, and rs3087459 are not Associated with Diabetic Nephropathy in Caucasians with Type 2 Diabetes Mellitus.PMID 28976905Read ↗

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