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Genetic susceptibility of five tagSNPs in the endothelin-1 (EDN1) gene to coronary artery disease in a Chinese Han population.

Bioscience reports - 31 Oct 2018

Liang Li-Li, Chen Lin, Zhou Meng-Yuan, Cai Meng-Yun, Cheng Jie, Chen Yi, You Si-Kun, Chen Lin-Bin, Tang Zi-Bin, Yang Xi-Li, Chen Can, Liu Xinguang, Xiong Xing-Dong

Abstract excerpt

Endothelin-1 (ET-1) plays important roles in endothelial dysfunction, vascular physiology, inflammation, and atherosclerosis. Nonetheless, the role of ET-1 (EDN1) gene variants on coronary artery disease (CAD) risk remains poorly understood. The aim of the present study was to evaluate the role of EDN1 gene polymorphisms on individual susceptibility to CAD. We genotyped five tagSNPs (single-nucleotide...

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Identifiers

PMID: 29654172
DOI: 10.1042/BSR20171320
PMCID: PMC6205642

Genes

CAD
EDN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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