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Article

Comparative analysis of editosome proteins in trypanosomatids

6 Nov 2003

Abstract excerpt

Detailed comparisons of 16 editosome proteins from Trypanosoma brucei, Trypanosoma cruzi and Leishmania major identified protein motifs associated with catalysis and protein or nucleic acid interactions that suggest their functions in RNA editing. Five related proteins with RNase III-like motifs also contain a U1-like zinc finger and either dsRBM or Pumilio motifs. These proteins may provide the endoribonuclease...

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PMID: 14602897
DOI: 10.1093/nar/gkg870

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