Article
Assembly and analysis of 100 full MHC haplotypes from the Danish population.
Genome research - 1 Sept 2017
Jensen Jacob M, Villesen Palle, Friborg Rune M, Mailund Thomas, Besenbacher Søren, Schierup Mikkel H
Abstract excerpt
Genes in the major histocompatibility complex (MHC, also known as HLA) play a critical role in the immune response and variation within the extended 4-Mb region shows association with major risks of many diseases. Yet, deciphering the underlying causes of these associations is difficult because the MHC is the most polymorphic region of the genome with a complex linkage disequilibrium structure. Here, we...
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