Article
State-of-the-art genome inference in the human MHC.
The international journal of biochemistry & cell biology - 1 Feb 2021
Dilthey Alexander T
Abstract excerpt
The Major Histocompatibility Complex (MHC) on the short arm of chromosome 6 is associated with more diseases than any other region of the genome; it encodes the antigen-presenting Human Leukocyte Antigen (HLA) proteins and is one of the key immunogenetic regions of the genome. Accurate genome inference and interpretation of MHC association signals have traditionally been hampered by the region's uniquely complex...
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