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Article

HLA diversity in the 1000 genomes dataset.

PloS one - 1 Jan 2014

Gourraud Pierre-Antoine, Khankhanian Pouya, Cereb Nezih, Yang Soo Young, Feolo Michael, Maiers Martin, Rioux John D, Hauser Stephen, Oksenberg Jorge

Abstract excerpt

The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation by sequencing at a level that should allow the genome-wide detection of most variants with frequencies as low as 1%. However, in the major histocompatibility complex (MHC), only the top 10 most frequent haplotypes are in the 1% frequency range whereas thousands of haplotypes are present at lower frequencies. Given...

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Share to Databases, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24988075
DOI: 10.1371/journal.pone.0097282
PMCID: PMC4079705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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