Article
Population-specific recombination sites within the human MHC region.
Heredity - 1 Aug 2013
Lam T H, Shen M, Chia J-M, Chan S H, Ren E C
Abstract excerpt
Genetic rearrangement by recombination is one of the major driving forces for genome evolution, and recombination is known to occur in non-random, discreet recombination sites within the genome. Mapping of recombination sites has proved to be difficult, particularly, in the human MHC region that is complicated by both population variation and highly polymorphic HLA genes. To overcome these problems, HLA-typed...
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