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Article

Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era

30 Jan 2025

Abstract excerpt

Barrett's esophagus (BE) represents a pre-cancerous condition that is characterized by the metaplastic conversion of the squamous esophageal epithelium to a columnar intestinal-like phenotype. BE is the consequence of chronic reflux disease and has a potential progression burden to esophageal adenocarcinoma (EAC). The pathogenesis of BE and EAC has been extensively studied but not completely understood, and it is...

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Identifiers

PMID: 39950103
DOI: 10.3389/fonc.2024.1458138

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