Article
Genomic similarity between gastroesophageal junction and esophageal Barrett's adenocarcinomas.
Oncotarget - 23 Aug 2016
Ferrer-Torres Daysha, Nancarrow Derek J, Kuick Rork, Thomas Dafydd G, Nadal Ernest, Lin Jules, Chang Andrew C, Reddy Rishindra M, Orringer Mark B, Taylor Jeremy M G, Wang Thomas D, Beer David G
Abstract excerpt
The current high mortality rate of esophageal adenocarcinoma (EAC) reflects frequent presentation at an advanced stage. Recent efforts utilizing fluorescent peptides have identified overexpressed cell surface targets for endoscopic detection of early stage Barrett's-derived EAC. Unfortunately, 30% of EAC patients present with gastroesophageal junction adenocarcinomas (GEJAC) and lack premalignant Barrett's...
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