Article
Fetal hemoglobin in sickle cell anemia: The Arab-Indian haplotype and new therapeutic agents.
American journal of hematology - 1 Nov 2017
Habara Alawi H, Shaikho Elmutaz M, Steinberg Martin H
Abstract excerpt
Fetal hemoglobin (HbF) has well-known tempering effects on the symptoms of sickle cell disease and its levels vary among patients with different haplotypes of the sickle hemoglobin gene. Compared with sickle cell anemia haplotypes found in patients of African descent, HbF levels in Saudi and Indian patients with the Arab-Indian (AI) haplotype exceed that in any other haplotype by nearly twofold. Genetic...
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