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Article

Fetal hemoglobin in sickle cell anemia.

Blood - 19 Nov 2020

Steinberg Martin H

Abstract excerpt

Fetal hemoglobin (HbF) can blunt the pathophysiology, temper the clinical course, and offer prospects for curative therapy of sickle cell disease. This review focuses on (1) HbF quantitative trait loci and the geography of β-globin gene haplotypes, especially those found in the Middle East; (2) how HbF might differentially impact the pathophysiology and many subphenotypes of sickle cell disease; (3) clinical...

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Identifiers

PMID: 32808012
DOI: 10.1182/blood.2020007645
PMCID: PMC7685210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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