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Article

Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences

20 Jul 2017

Abstract excerpt

The human CST (CTC1-STN1-TEN1) heterotrimeric complex plays roles in both telomere maintenance and DNA replication through its ability to interact with single-stranded DNA (ssDNA) of a variety of sequences. The precise sequence specificity required to execute these functions is unknown. Telomere-binding proteins have been shown to specifically recognize key telomeric sequence motifs within ssDNA while...

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Share to Advanced biosensing and bioanalysis techniques
Share to DNA Repair Mechanisms
Share to Telomeres, Telomerase, and Senescence

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PMID: 28726394
DOI: 10.1021/acs.biochem.7b00584

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