Article
HLA-check: evaluating HLA data from SNP information.
BMC bioinformatics - 11 Jul 2017
Jeanmougin Marc, Noirel Josselin, Coulonges Cédric, Zagury Jean-François
Abstract excerpt
BACKGROUND: The major histocompatibility complex (MHC) region of the human genome, and specifically the human leukocyte antigen (HLA) genes, play a major role in numerous human diseases. With the recent progress of sequencing methods (eg, Next-Generation Sequencing, NGS), the accurate genotyping of this region has become possible but remains relatively costly. In order to obtain the HLA information for the...
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