Article
Deep Learning-Based HLA Allele Imputation Applicable to GWAS.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024
Naito Tatsuhiko
Abstract excerpt
Human leukocyte antigen (HLA) imputation is an essential step following genome-wide association study, particularly when putative associations in HLA genes are identified, to fully understand the genetic basis of human traits. Different HLA imputation methods have been developed, each with its own advantages, and recent methods have been improved in terms of imputation accuracy and computational costs. Here, I...
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