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Article

Dense Genotyping of Immune-Related Regions Identifies Loci for Rheumatoid Arthritis Risk and Damage in African Americans.

Molecular medicine (Cambridge, Mass.) - 1 Sept 2017

Danila Maria I, Laufer Vincent Albert, Reynolds Richard J, Yan Qi, Liu Nianjun, Gregersen Peter K, Lee Annette, Kern Marlena, Langefeld Carl D, Arnett Donna K, Bridges S Louis

Abstract excerpt

Over 100 risk loci for rheumatoid arthritis (RA) have been identified in individuals of European and Asian descent, but the genetic basis for RA in African Americans is less well understood. We genotyped 610 African Americans with autoantibody positive RA and 933 African American controls on the ImmunoChip (iChip) array. Using multivariable regression we evaluated the association between iChip markers and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28681901
DOI: 10.2119/molmed.2017.00081
PMCID: PMC5583066

Genes

AFF3
ETS1
CTLA4
TNFRSF9
TNFSF11
TNFSF18
TRAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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