Article
Association of single-nucleotide polymorphisms in CCR6, TAGAP, and TNFAIP3 with rheumatoid arthritis in African Americans.
Arthritis and rheumatism - 1 May 2012
Perkins Elizabeth A, Landis Dawn, Causey Zenoria L, Edberg Yuanqing, Reynolds Richard J, Hughes Laura B, Gregersen Peter K, Kimberly Robert P, Edberg Jeffrey C, Bridges S Louis
Abstract excerpt
OBJECTIVE: We previously reported an analysis of single-nucleotide polymorphisms (SNPs) in 3 validated European rheumatoid arthritis (RA) susceptibility loci, TAGAP, TNFAIP3, and CCR6, in African American patients with RA. Unexpectedly, the disease-associated alleles were different in African Americans from those in Europeans. In an effort to better define their contribution, we performed additional SNP...
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