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Article

A role for nonessential domain II of initiator protein, DnaA, in replication control.

Genetics - 1 Sept 2009

Molt Kathryn L, Sutera Vincent A, Moore Kathryn K, Lovett Susan T

Abstract excerpt

The initiation of replication in bacteria is regulated via the initiator protein DnaA. ATP-bound DnaA binds to multiple sequences at the origin of replication, oriC, unwinding the DNA and promoting the binding of DnaB helicase. From an Escherichia coli mutant highly perturbed for replication control, obgE::Tn5-EZ seqADelta, we isolated multiple spontaneous suppressor mutants with enhanced growth and viability....

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Identifiers

PMID: 19546317
DOI: 10.1534/genetics.109.104760
PMCID: PMC2746162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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