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Article

DNA replication in Escherichia coli is initiated by membrane detachment of oriC. A model.

Journal of molecular biology - 5 Sept 1990

Norris V

Abstract excerpt

An adequate model for the initiation of chromosome replication in Escherichia coli should explain why the introduction of multiple copies of the chromosomal origin of replication, oriC, does not perturb cells seriously and why such multiple origins are replicated synchronously; it should explain why the key initiator protein, DnaA, is activated in vitro by binding specifically to acidic phospholipids and why the...

Topics

Cell Cycle
Cell Membrane
Chromosomes, Bacterial
DNA Replication
DNA, Bacterial
DNA, Superhelical
DNA-Directed RNA Polymerases
Escherichia coli
Genes, Bacterial
Methylation
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

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Identifiers

PMID: 2204708
DOI: 10.1016/s0022-2836(05)80095-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2204708-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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DNA replication in Escherichia coli is initiated by membrane detachment of oriC. A model.PMID 2204708Read ↗

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