Article
Error-prone DNA polymerases: when making a mistake is the only way to get ahead.
Annual review of genetics - 1 Jan 2003
Rattray Alison J, Strathern Jeffrey N
Abstract excerpt
Cells have high-fidelity polymerases whose task is to accurately replicate the genome, and low-fidelity polymerases with specialized functions. Although some of these low-fidelity polymerases are exceptional in their ability to replicate damaged DNA and restore the undamaged sequence, they are error prone on undamaged DNA. In fact, these error-prone polymerases are sometimes used in circumstances where the...
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