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Article

Polymorphic variants of Caspase genes (8 & 3) in the risk prediction of Coronary Artery Disease.

Gene - 5 Sept 2017

Gundapaneni Kishore Kumar, Shyamala Nivas, Galimudi Rajesh Kumar, Kupsal Keerthi, Gantala Srilatha Reddy, Padala Chiranjeevi, Gunda Padma, Tupurani Mohini Aiyengar, Puranam Kaushik, Sahu Sanjib Kumar, Hanumanth Surekha Rani

Abstract excerpt

Apoptosis has been involved in a number of pathological conditions including coronary artery disease (CAD). Caspases (CASP) are important regulators and executioners in both extrinsic and intrinsic apoptotic pathways. The aim of the present study is to examine the role of Caspase 8 and 3 polymorphisms in the pathogenesis of CAD. CAD patients (n=300) and healthy controls (n=300) were genotyped for polymorphisms in...

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Identifiers

PMID: 28633917
DOI: 10.1016/j.gene.2017.06.035

Genes

CAD
CASP8
CASP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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