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Article

Influence of genetic polymorphism in matrix metalloproteinase-3 on extent of coronary atherosclerosis and risk of coronary artery stenosis.

Archives of medical research - 1 Oct 2009

Seifi Morteza, Fallah Soudabeh, Firoozrai Mohsen

Abstract excerpt

BACKGROUND AND AIMS: Matrix metalloproteinase-3 (MMP3) is key member of the MMP family. It is known to be present in coronary atherosclerosis. Several studies have demonstrated that MMP-3 5A/6A polymorphism modifies each transcriptional activity in an allele-specific manner. We hypothesized that this polymorphism may be a risk factor for the development of coronary artery stenosis (CAS). We estimated the effect...

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Source

Identifiers

PMID: 20082876
DOI: 10.1016/j.arcmed.2009.08.008

Genes

MMP3

Provenance

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