Article
Variations in matrix metalloproteinase-1, -3, and -9 genes and the risk of acute coronary syndrome and coronary artery disease in the Chinese Han population.
Coronary artery disease - 1 Jun 2013
Xu Xin, Wang Lihan, Xu Changfu, Zhang Peng, Yong Fendi, Liu Haibo, Wang Jianan, Shi Yuping
Abstract excerpt
OBJECTIVES: Matrix metalloproteinases (MMPs) are a group of endopeptidases involved in the pathogenesis of atherosclerosis, and MMP gene polymorphisms may contribute toward the risk of coronary heart disease. Within this context, our aim was to examine whether MMP1, MMP3, and MMP9 gene polymorphisms are associated with susceptibility to acute coronary syndrome (ACS) or angiographic coronary artery disease (CAD)....
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