Article
Intronic Polymorphisms in the CDKN2B-AS1 Gene Are Strongly Associated with the Risk of Myocardial Infarction and Coronary Artery Disease in the Saudi Population.
International journal of molecular sciences - 17 Mar 2016
AbdulAzeez Sayed, Al-Nafie Awatif N, Al-Shehri Abdullah, Borgio J Francis, Baranova Ekaterina V, Al-Madan Mohammed S, Al-Ali Rudaynah A, Al-Muhanna Fahad, Al-Ali Abdullah, Al-Mansori Mohammed, Ibrahim Mohammed Fakhry, Asselbergs Folkert W, Keating Brendan, Koeleman Bobby P C, Al-Ali Amein K
Abstract excerpt
Recent genome-wide association studies identified single nucleotide polymorphisms (SNPs) on the chromosome 9p21.3 conferring the risk for CAD (coronary artery disease) in individuals of Caucasian ancestry. We performed a genetic association study to investigate the effect of 12 candidate SNPs within 9p21.3 locus on the risk of CAD in the Saudi population of the Eastern Province of Saudi Arabia. A total of 250...
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