Article
Haplotypes and 5A/6A polymorphism of the matrix metalloproteinase-3 gene in coronary disease: case-control study and a meta-analysis.
Atherosclerosis - 1 Jan 2010
Koch Werner, de Waha Antoinette, Hoppmann Petra, Schömig Albert, Kastrati Adnan
Abstract excerpt
OBJECTIVE: Matrix metalloproteinase-3 and its gene, MMP3, have been implicated in atherosclerotic diseases of coronary arteries. We conducted a haplotype analysis to examine the role of common variation of MMP3 in myocardial infarction (MI) and a meta-analysis to combine available evidence on the association between the 5A/6A polymorphism (rs3025058) and coronary diseases. METHODS AND RESULTS: Genotype...
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