Article
Protective effect of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 haplotype on coronary artery disease.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 2017
Lasom Supakanya, Komanasin Nantarat, Settasatian Nongnuch, Settasatian Chatri, Kukongviriyapan Upa, Intharapetch Pongsak, Senthong Vichai
Abstract excerpt
: Genetic variations of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) and von Willebrand factor (vWF) were related to ADAMTS13 levels. Reduction of ADAMTS13 activity may affect atherosclerotic progression. However, the associations of polymorphisms of these genes with coronary artery disease (CAD) are still unclear. This study, therefore, aimed to investigate the...
Topics
- ADAMTS13 Protein
- Amino Acid Motifs
- Case-Control Studies
- Coronary Artery Disease
- Disintegrins
- Female
- Genetic Variation
- Haplotypes
- Humans
- Male
- Metalloproteases
- Middle Aged
- Polymorphism, Single Nucleotide