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Article

The NLRP3 and CASP1 gene polymorphisms are associated with developing of acute coronary syndrome: a case-control study.

Immunologic research - 1 Aug 2017

Gonzalez-Pacheco Hector, Vargas-Alarcon Gilberto, Angeles-Martinez Javier, Martinez-Sanchez Carlos, Perez-Mendez Oscar, Herrera-Maya Gabriel, Martinez-Rios Marco Antonio, Peña-Duque Marco Antonio, Posadas-Romero Carlos, Fragoso Jose Manuel

Abstract excerpt

The protein products of NLRP3 and CASP1 genes are involved in the cleavage of pro-IL-1B and pro-IL-18 leading to the active cytokines, which play an important role in the development of the acute coronary syndrome (ACS). The aim of the present study was to evaluate whether NLRP3 and CASP1 gene polymorphisms are biomarkers of ACS susceptibility in Mexican population. Two polymorphisms of the CASP1 gene [G+7/in6A...

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Identifiers

PMID: 28456882
DOI: 10.1007/s12026-017-8924-0

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CASP1
NLRP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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