Article
Genetic score based on high-risk genetic polymorphisms and early onset of ischemic heart disease in an Italian cohort of ischemic patients.
Thrombosis research - 1 May 2014
Vecoli Cecilia, Adlerstein Daniel, Shehi Erlet, Bigazzi Federico, Sampietro Tiziana, Foffa Ilenia, Carpeggiani Clara, L'abbate Antonio, Andreassi Maria Grazia
Abstract excerpt
Several single-nucleotide polymorphisms (SNPs) have been recognized as associated with ischemic heart disease (IHD) although the optimal set of risk genotypes has not be identified. This study aimed to examine whether identified high-risk SNPs are associated with early onset of IHD. In the GENOCOR study, 44 high-risk SNPs were genotyped in 114 patients with early onset of IHD (46.2 ± 5.1 years) and 384 patients...
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